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Late diagnosis of Lesch-Nyhan disease variant

A 30-year-old man was referred for investigation and management of hyperuricaemia. History included recurrent nephrolithiasis and chronic gout with poor response to medical management. Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) enzyme activity was investigated and found to be deficient c...

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Библиографические подробности
Главные авторы: Doucet, Brian Percy, Jegatheesan, Dev, Burke, John
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Publishing Group 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863095/
https://ncbi.nlm.nih.gov/pubmed/24326440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bcr-2013-201997
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