A mutation that alters magnesium block of N-methyl-D-aspartate receptor channels.
N-Methyl-D-aspartate (NMDA) receptors are blocked at hyperpolarizing potentials by extracellular Mg ions. Here we present a detailed kinetic analysis of the Mg block in recombinant wild-type and mutant NMDA receptors. We find that the Mg binding site is the same in the wild-type and native hippocamp...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
1996
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38629/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8799188/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.17.9259 |
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