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Inhibition of the early asthmatic response to inhaled allergen by the 5-lipoxygenase activating protein inhibitor GSK2190915: a dose–response study

BACKGROUND: GSK2190915, a 5-lipoxygenase activating protein inhibitor, inhibits the production of cysteinyl leukotrienes and leukotriene B4 and 5-oxo-6,8,11,14-eicosatetraenoic acid. We have previously reported that GSK2190915 100 mg daily inhibits early and late asthmatic responses to inhaled aller...

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Detalhes bibliográficos
Main Authors: Singh, Dave, Boyce, Malcolm, Norris, Virginia, Kent, Sandra E, Bentley, Jane H
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862733/
https://ncbi.nlm.nih.gov/pubmed/24357936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJGM.S51364
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