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New prospects on the NKG2D/NKG2DL system for oncology

The activating immunoreceptor NKG2D endows cytotoxic lymphocytes with the capacity to recognize and eliminate infected or malignant cells. The recognition of such harmful cells is enabled by binding of NKG2D to various MHC class I-related glycoproteins, which are upregulated in the course of viral i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ullrich, Evelyn, Koch, Joachim, Cerwenka, Adelheid, Steinle, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862635/
https://ncbi.nlm.nih.gov/pubmed/24353908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.26097
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