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Relative level of thiabendazole resistance associated with the E198A and F200Y SNPs in larvae of a multi-drug resistant isolate of Haemonchus contortus

While the F200Y SNP in the beta-tubulin gene is most commonly associated with benzimidazole resistance in trichostrongylid nematodes, other SNPs as well as drug efflux pathways have been implicated in the resistance. The relative contributions of all these mechanisms are not understood sufficiently...

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Autori principali: Kotze, Andrew C., Cowling, Katie, Bagnall, Neil H., Hines, Barney M., Ruffell, Angela P., Hunt, Peter W., Coleman, Glen T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862426/
https://ncbi.nlm.nih.gov/pubmed/24533269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2012.02.003
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