Polymorphism in dhfr/dhps genes, parasite density and ex vivo response to pyrimethamine in Plasmodium falciparum malaria parasites in Thies, Senegal()

Resistance to sulfadoxine–pyrimethamine (SP) in Plasmodium falciparum malaria parasites is associated with mutations in the dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes, and these mutations have spread resistance worldwide. SP, used for several years in Senegal, has been...

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Autores principales: Ndiaye, Daouda, Dieye, Baba, Ndiaye, Yaye D., Tyne, Daria Van, Daniels, Rachel, Bei, Amy K., Mbaye, Aminata, Valim, Clarissa, Lukens, Amanda, Mboup, Souleymane, Ndir, Omar, Wirth, Dyann F., Volkman, Sarah
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862402/
https://ncbi.nlm.nih.gov/pubmed/24533303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2013.07.001
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