A clinical exploratory study with itolizumab, an anti-CD6 monoclonal antibody, in patients with rheumatoid arthritis

T cells are involved in the pathogenesis of rheumatoid arthritis (RA). CD6 is a co-stimulatory molecule, predominantly expressed on lymphocytes, that has been linked to autoreactive responses. The purpose of this study was to evaluate the safety, immunogenicity and preliminary efficacy of itolizumab...

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Hoofdauteurs: Rodriguez, Pedro C., Torres-Moya, Roberto, Reyes, Gil, Molinero, Claudino, Prada, Dinorah, Lopez, Ana M., Hernandez, Isabel M., Hernandez, Maria V., Martinez, Jose P., Hernandez, Xochel, Casaco, Angel, Ramos, Mayra, Avila, Yisel, Barrese, Yinet, Montero, Enrique, Hernandez, Patricia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862386/
https://ncbi.nlm.nih.gov/pubmed/24371585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rinim.2012.11.001
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