IgM phosphorylcholine antibodies inhibit cell death and constitute a strong protection marker for atherosclerosis development, particularly in combination with other auto-antibodies against modified LDL

BACKGROUND: We have reported that anti-phosphorylcholine (anti-PC) IgM is a protection marker for human cardiovascular disease (CVD) and atherosclerosis. We here investigate the anti-PC autoantibodies in a well-defined cohort with regard to idiotype, atherosclerosis progression and mechanisms for it...

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Detalhes bibliográficos
Main Authors: Fiskesund, Roland, Su, Jun, Bulatovic, Ivana, Vikström, Max, de Faire, Ulf, Frostegård, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862347/
https://ncbi.nlm.nih.gov/pubmed/24371562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rinim.2012.01.001
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