Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites.

Mutations in the recently identified presenilin 1 gene on chromosome 14 cause early onset familial Alzheimer disease (FAD). Herein we describe the expression and analysis of the protein coded by presenilin 1 (PS1) in NT2N neurons, a human neuronal model system. PS1 was expressed using recombinant Se...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Cook, D G, Sung, J C, Golde, T E, Felsenstein, K M, Wojczyk, B S, Tanzi, R E, Trojanowski, J Q, Lee, V M, Doms, R W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38623/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8799182/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.17.9223
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