Homeostatic Control of Synaptic Activity by Endogenous Adenosine is Mediated by Adenosine Kinase

Extracellular adenosine, a key regulator of neuronal excitability, is metabolized by astrocyte-based enzyme adenosine kinase (ADK). We hypothesized that ADK might be an upstream regulator of adenosine-based homeostatic brain functions by simultaneously affecting several downstream pathways. We there...

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Detalhes bibliográficos
Main Authors: Diógenes, Maria José, Neves-Tomé, Raquel, Fucile, Sergio, Martinello, Katiuscia, Scianni, Maria, Theofilas, Panos, Lopatář, Jan, Ribeiro, Joaquim A., Maggi, Laura, Frenguelli, Bruno G., Limatola, Cristina, Boison, Detlev, Sebastião, Ana M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862265/
https://ncbi.nlm.nih.gov/pubmed/22997174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhs284
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