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The Antidepressant Desipramine and α(2)-Adrenergic Receptor Activation Promote Breast Tumor Progression in Association with Altered Collagen Structure

Emotional stress activates the sympathetic nervous system (SNS) and release of the neurotransmitter norepinephrine (NE) to promote breast tumor pathogenesis. We demonstrate here that the metastatic mammary adenocarcinoma cell line 4T1 does not express functional adrenergic receptors (AR), the recept...

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Detalhes bibliográficos
Main Authors: Szpunar, Mercedes J., Burke, Kathleen A., Dawes, Ryan P., Brown, Edward B., Madden, Kelley S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862035/
https://ncbi.nlm.nih.gov/pubmed/24309563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0079
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