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Silencing the Menkes Copper-Transporting ATPase (Atp7a) Gene in Rat Intestinal Epithelial (IEC-6) Cells Increases Iron Flux via Transcriptional Induction of Ferroportin 1 (Fpn1)(1)(2)(3)
The Menkes copper-transporting ATPase (Atp7a) gene is induced in rat duodenum during iron deficiency, consistent with copper accumulation in the intestinal mucosa and liver. To test the hypothesis that ATP7A influences intestinal iron metabolism, the Atp7a gene was silenced in rat intestinal epithel...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Nutrition
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3861793/ https://ncbi.nlm.nih.gov/pubmed/24174620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.113.183160 |
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