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Skeletal Muscle-derived Myonectin Activates the Mammalian Target of Rapamycin (mTOR) Pathway to Suppress Autophagy in Liver

Cells turn on autophagy, an intracellular recycling pathway, when deprived of nutrients. How autophagy is regulated by hormonal signals in response to major changes in metabolic state is not well understood. Here, we provide evidence that myonectin (CTRP15), a skeletal muscle-derived myokine, is a n...

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Detalhes bibliográficos
Main Authors: Seldin, Marcus M., Lei, Xia, Tan, Stefanie Y., Stanson, Kevin P., Wei, Zhikui, Wong, G. William
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861655/
https://ncbi.nlm.nih.gov/pubmed/24187137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.500736
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