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NAT8L (N-Acetyltransferase 8-Like) Accelerates Lipid Turnover and Increases Energy Expenditure in Brown Adipocytes

NAT8L (N-acetyltransferase 8-like) catalyzes the formation of N-acetylaspartate (NAA) from acetyl-CoA and aspartate. In the brain, NAA delivers the acetate moiety for synthesis of acetyl-CoA that is further used for fatty acid generation. However, its function in other tissues remained elusive. Here...

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Detalhes bibliográficos
Main Authors: Pessentheiner, Ariane R., Pelzmann, Helmut J., Walenta, Evelyn, Schweiger, Martina, Groschner, Lukas N., Graier, Wolfgang F., Kolb, Dagmar, Uno, Kyosuke, Miyazaki, Toh, Nitta, Atsumi, Rieder, Dietmar, Prokesch, Andreas, Bogner-Strauss, Juliane G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861652/
https://ncbi.nlm.nih.gov/pubmed/24155240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.491324
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