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Kinetics of allosteric transitions in S-adenosylmethionine riboswitch are accurately predicted from the folding landscape
Riboswitches are RNA elements that allosterically regulate gene expression by binding cellular metabolites. The SAM-III riboswitch, one of several classes that binds S-adenosylmethionine (SAM), represses translation upon binding SAM (OFF state) by encrypting the ribosome binding sequence. We have ca...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3861500/ https://ncbi.nlm.nih.gov/pubmed/24087850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja408595e |
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