KIR, HLA, and IL28B Variant Predict Response to Antiviral Therapy in Genotype 1 Chronic Hepatitis C Patients in Japan

Natural killer cell responses play a crucial role in virus clearance by the innate immune system. Although the killer immunoglobulin-like receptor (KIR) in combination with its cognate human leukocyte antigen (HLA) ligand, especially KIR2DL3-HLA-C1, is associated with both treatment-induced and spon...

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Main Authors: Nozawa, Yuichi, Umemura, Takeji, Joshita, Satoru, Katsuyama, Yoshihiko, Shibata, Soichiro, Kimura, Takefumi, Morita, Susumu, Komatsu, Michiharu, Matsumoto, Akihiro, Tanaka, Eiji, Ota, Masao
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861489/
https://ncbi.nlm.nih.gov/pubmed/24349500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083381
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