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Hypoxic Tumor Environments Exhibit Disrupted Collagen I Fibers and Low Macromolecular Transport

Hypoxic tumor microenvironments result in an aggressive phenotype and resistance to therapy that lead to tumor progression, recurrence, and metastasis. While poor vascularization and the resultant inadequate drug delivery are known to contribute to drug resistance, the effect of hypoxia on molecular...

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מידע ביבליוגרפי
Main Authors: Kakkad, Samata M., Penet, Marie-France, Akhbardeh, Alireza, Pathak, Arvind P., Solaiyappan, Meiyappan, Raman, Venu, Leibfritz, Dieter, Glunde, Kristine, Bhujwalla, Zaver M.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861360/
https://ncbi.nlm.nih.gov/pubmed/24349142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081869
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