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The spatial segregation of pericentric cohesin and condensin in the mitotic spindle

In mitosis, the pericentromere is organized into a spring composed of cohesin, condensin, and a rosette of intramolecular chromatin loops. Cohesin and condensin are enriched in the pericentromere, with spatially distinct patterns of localization. Using model convolution of computer simulations, we d...

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Main Authors: Stephens, Andrew D., Quammen, Cory W., Chang, Binny, Haase, Julian, Taylor, Russell M., Bloom, Kerry
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861086/
https://ncbi.nlm.nih.gov/pubmed/24152737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-06-0325
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