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Exploring Early Stages of the Chemical Unfolding of Proteins at the Proteome Scale
After decades of using urea as denaturant, the kinetic role of this molecule in the unfolding process is still undefined: does urea actively induce protein unfolding or passively stabilize the unfolded state? By analyzing a set of 30 proteins (representative of all native folds) through extensive mo...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3861036/ https://ncbi.nlm.nih.gov/pubmed/24348236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003393 |
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