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CYP2C19*2/ABCB1-C3435T polymorphism and risk of cardiovascular events in coronary artery disease patients on clopidogrel: Is clinical testing helpful?

BACKGROUND: Studies evaluating CYP2C19*2 and ABCB1-C3435T polymorphisms have shown conflicting results. We performed this meta-analysis to evaluate role of clinical testing for these polymorphisms in CAD patients on clopidogrel. METHODS: 19,601 patients from 14 trials were analyzed. The endpoints we...

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Detalhes bibliográficos
Main Authors: Singh, Mukesh, Shah, Tejaskumar, Adigopula, Sasikanth, Molnar, Janos, Ahmed, Aziz, Khosla, Sandeep, Arora, Rohit
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3860862/
https://ncbi.nlm.nih.gov/pubmed/22929815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ihj.2012.06.003
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