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Phosphorylation by protein kinase C of serine-23 of the alpha-1 subunit of rat Na+,K(+)-ATPase affects its conformational equilibrium.

Phosphorylation of the alpha-1 subunit of rat Na+,K(+)-ATPase by protein kinase C has been shown previously to decrease the activity of the enzyme in vitro. We have now undertaken an investigation of the mechanism by which this inhibition occurs. Analysis of the phosphorylation of recombinant glutat...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Logvinenko, N S, Dulubova, I, Fedosova, N, Larsson, S H, Nairn, A C, Esmann, M, Greengard, P, Aperia, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38607/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8799166/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.17.9132
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