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OPA1 downregulation is involved in sorafenib-induced apoptosis in hepatocellular carcinoma
Sorafenib has been used to treat advanced hepatocellular carcinoma (HCC), but the underlying molecular mechanisms remain controversial and why some patients do not respond to this therapy is poorly understood. In this study, we show that sorafenib triggers cell growth inhibition and apoptosis in HCC...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3860369/ https://ncbi.nlm.nih.gov/pubmed/23108376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2012.144 |
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