Phase-II study of dose attenuated schedule of irinotecan, capecitabine, and celecoxib in advanced colorectal cancer

BACKGROUND: The cyclooxygenase-2 (COX-2) enzyme plays a major role in tumor progression and resistance to chemotherapy. A Phase-II study was undertaken to determine the activity of a dose attenuated schedule of irinotecan, capecitabine, and the COX-2 inhibitor celecoxib in patients with advanced col...

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Main Authors: El-Rayes, Bassel F., Zalupski, Mark M., Manza, Stephanie G., Rusin, Barbara, Ferris, Ann Marie, Vaishampayan, Ulka, Heilbrun, Lance K., Venkatramanamoorthy, Raghu, Shields, Anthony F., Philip, Philip A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2007
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3860285/
https://ncbi.nlm.nih.gov/pubmed/17429629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-007-0472-1
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