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The effects of tolvaptan on patients with severe chronic kidney disease complicated by congestive heart failure

BACKGROUND: Tolvaptan, a diuretic with a new mechanism of action, selectively binds to the vasopressin V2 receptor and inhibits reabsorption of water. Its effect on heart failure is proven, but its benefit for patients with chronic kidney disease (CKD) has not been not confirmed. In this study, we e...

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Detalhes bibliográficos
Main Authors: Otsuka, Tomoyuki, Sakai, Yukinao, Ohno, Dai, Murasawa, Tsuneo, Sato, Naoki, Tsuruoka, Shuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859890/
https://ncbi.nlm.nih.gov/pubmed/23483323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10157-013-0788-6
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