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Alternative Polyadenylation and miR-34 Family Members Regulate Tau Expression

Tau pathologically aggregates in Alzheimer’s disease, and evidence suggests that reducing tau expression may be safe and beneficial for the prevention or treatment of this disease. We sought to examine the role of the 3’-untranslated region (3’-UTR) of human tau mRNA in regulating tau expression. Ta...

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Detalhes bibliográficos
Main Authors: Dickson, John R., Kruse, Carla, Montagna, Daniel R., Finsen, Bente, Wolfe, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859707/
https://ncbi.nlm.nih.gov/pubmed/24032460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12437
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