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Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage lambda transgene target.

Genetic instability is thought to be responsible for the numerous genotypic changes that occur during neoplastic transformation and metastatic progression. To explore the role of genetic instability at the level of point mutations during mammary tumor development and malignant progression, we combin...

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Опубликовано в::Proc Natl Acad Sci U S A
Главные авторы: Jakubczak, J L, Merlino, G, French, J E, Muller, W J, Paul, B, Adhya, S, Garges, S
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1996
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38597/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8799156/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.17.9073
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