New Therapeutic Approach: Diphenyl Diselenide Reduces Mitochondrial Dysfunction in Acetaminophen-Induced Acute Liver Failure

The acute liver failure (ALF) induced by acetaminophen (APAP) is closely related to oxidative damage and depletion of hepatic glutathione, consequently changes in cell energy metabolism and mitochondrial dysfunction have been observed after APAP overdose. Diphenyl diselenide [(PhSe)(2)], a simple or...

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Autori principali: Carvalho, Nélson R., da Rosa, Edovando F., da Silva, Michele H., Tassi, Cintia C., Dalla Corte, Cristiane L., Carbajo-Pescador, Sara, Mauriz, Jose L., González-Gallego, Javier, Soares, Félix A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859582/
https://ncbi.nlm.nih.gov/pubmed/24349162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081961
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