Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis

Protection against deadly pathogens requires the production of high-affinity antibodies by B cells, which are generated in germinal centers (GCs). Alteration of the GC developmental program is common in many B cell malignancies. Identification of regulators of the GC response is crucial to develop t...

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Main Authors: Caganova, Marieta, Carrisi, Chiara, Varano, Gabriele, Mainoldi, Federica, Zanardi, Federica, Germain, Pierre-Luc, George, Laura, Alberghini, Federica, Ferrarini, Luca, Talukder, Asoke K., Ponzoni, Maurilio, Testa, Giuseppe, Nojima, Takuya, Doglioni, Claudio, Kitamura, Daisuke, Toellner, Kai-M., Su, I-hsin, Casola, Stefano
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859423/
https://ncbi.nlm.nih.gov/pubmed/24200695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70626
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