Inhibition of Coxsackievirus-associated dystrophin cleavage prevents cardiomyopathy

Heart failure in children and adults is often the consequence of myocarditis associated with Coxsackievirus (CV) infection. Upon CV infection, enteroviral protease 2A cleaves a small number of host proteins including dystrophin, which links actin filaments to the plasma membrane of muscle fiber cell...

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Detalhes bibliográficos
Main Authors: Lim, Byung-Kwan, Peter, Angela K., Xiong, Dingding, Narezkina, Anna, Yung, Aaron, Dalton, Nancy D., Hwang, Kyung-Kuk, Yajima, Toshitaka, Chen, Ju, Knowlton, Kirk U.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859391/
https://ncbi.nlm.nih.gov/pubmed/24200690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66271
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