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Topical hypochlorite ameliorates NF-κB–mediated skin diseases in mice

Nuclear factor-κB (NF-κB) regulates cellular responses to inflammation and aging, and alterations in NF-κB signaling underlie the pathogenesis of multiple human diseases. Effective clinical therapeutics targeting this pathway remain unavailable. In primary human keratinocytes, we found that hypochlo...

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Bibliografske podrobnosti
Main Authors: Leung, Thomas H., Zhang, Lillian F., Wang, Jing, Ning, Shoucheng, Knox, Susan J., Kim, Seung K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859383/
https://ncbi.nlm.nih.gov/pubmed/24231355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70895
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