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Cell number changes in Alzheimer’s disease relate to dementia, not to plaques and tangles

Alzheimer’s disease is the commonest cause of dementia in the elderly, but its pathological determinants are still debated. Amyloid-β plaques and neurofibrillary tangles have been implicated either directly as disruptors of neural function, or indirectly by precipitating neuronal death and thus caus...

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Главные авторы: Andrade-Moraes, Carlos Humberto, Oliveira-Pinto, Ana V., Castro-Fonseca, Emily, da Silva, Camila G., Guimarães, Daniel M., Szczupak, Diego, Parente-Bruno, Danielle R., Carvalho, Ludmila R.B., Polichiso, Lívia, Gomes, Bruna V., Oliveira, Lays M., Rodriguez, Roberta D., Leite, Renata E.P., Ferretti-Rebustini, Renata E.L., Jacob-Filho, Wilson, Pasqualucci, Carlos A., Grinberg, Lea T., Lent, Roberto
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859218/
https://ncbi.nlm.nih.gov/pubmed/24136825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awt273
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