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Cell number changes in Alzheimer’s disease relate to dementia, not to plaques and tangles
Alzheimer’s disease is the commonest cause of dementia in the elderly, but its pathological determinants are still debated. Amyloid-β plaques and neurofibrillary tangles have been implicated either directly as disruptors of neural function, or indirectly by precipitating neuronal death and thus caus...
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| Главные авторы: | , , , , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3859218/ https://ncbi.nlm.nih.gov/pubmed/24136825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awt273 |
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