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Scavenger Receptor B and CD36 Targeting Improves Sepsis Survival and Acute Outcomes in Mice

Class B scavenger receptors, such as SR-BI/II or CD36, bind lipoproteins, but also mediate bacterial recognition and phagocytosis. In evaluating whether blocking receptors can prevent intracellular bacterial proliferation, phagocyte cytotoxicity and proinflammatory signaling in bacterial infection/s...

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Bibliographische Detailangaben
Hauptverfasser: Leelahavanichkul, Asada, Bocharov, Alexander V., Kurlander, Roger, Baranova, Irina N., Vishnyakova, Tatyana G., Souza, Ana C.P., Hu, Xuzhen, Doi, Kent, Vaisman, Boris, Amar, Marcelo, Sviridov, Denis, Chen, Zhigang, Remaley, Alan T., Csako, Gyorgy, Patterson, Amy P., Yuen, Peter S. T., Star, Robert A, Eggerman, Thomas L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859147/
https://ncbi.nlm.nih.gov/pubmed/22327076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003445
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