Hepatitis B Virus X Protein Inhibits Tumor Suppressor miR-205 through Inducing Hypermethylation of miR-205 Promoter to Enhance Carcinogenesis

The infection of hepatitis B virus (HBV) is closely associated with the development of hepatocellular carcinoma (HCC), in which HBV X protein (HBx) plays crucial roles. MicroRNAs are involved in diverse biologic functions and in carcinogenesis by regulating gene expression. In the present study, we...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Tao, Zhang, Junping, Cui, Ming, Liu, Fabao, You, Xiaona, Du, Yumei, Gao, Yuen, Zhang, Shuai, Lu, Zhanping, Ye, Lihong, Zhang, Xiaodong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858896/
https://ncbi.nlm.nih.gov/pubmed/24339740
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