Defects in Synapse Structure and Function Precede Motor Neuron Degeneration in Drosophila Models of FUS-Related ALS

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease that leads invariably to fatal paralysis associated with motor neuron degeneration and muscular atrophy. One gene associated with ALS encodes the DNA/RNA-binding protein Fused in Sarcoma (FUS). There now exist two Drosop...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Shahidullah, Mohammad, Le Marchand, Sylvain J., Fei, Hong, Zhang, Jiaming, Pandey, Udai Bhan, Dalva, Matthew B., Pasinelli, Piera, Levitan, Irwin B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2013
Soggetti:
Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858628/
https://ncbi.nlm.nih.gov/pubmed/24336723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3396-13.2013
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi