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Metabolic Flux Between Unsaturated and Saturated Fatty Acids is Controlled by the FabA:FabB Ratio in the Fully Reconstituted Fatty Acid Biosynthetic Pathway of E. coli()

The entire fatty acid biosynthetic pathway from Escherichia coli, starting from the acetyl-CoA carboxylase, has been reconstituted in vitro from fourteen purified protein components. Radiotracer analysis verified stoichiometric conversion of acetyl-CoA and NAD(P)H into the free fatty acid product, a...

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Detalhes bibliográficos
Main Authors: Xiao, Xirui, Yu, Xingye, Khosla, Chaitan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858588/
https://ncbi.nlm.nih.gov/pubmed/24147979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401116n
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