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Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation

Basic fibroblast growth factor (bFGF) has been implicated in tumor growth via interactions with its receptors (FGFRs) on the cell surface and therefore, bFGF/FGFRs are considered essential targets for cancer therapy. Herein, a consensus heptapeptide (LSPPRYP) was identified for the first time from a...

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Bibliografski detalji
Glavni autori: Wu, Xiaoping, Huang, Huixian, Wang, Cong, Lin, Shaoqiang, Huang, Yadong, Wang, Yi, Liang, Guang, Yan, Qiuxia, Xiao, Jian, Wu, Jianzhang, Yang, Yongguang, Li, Xiaokun
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858566/
https://ncbi.nlm.nih.gov/pubmed/24142482
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