Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer

Histone variants seem to play a major role in gene expression regulation. In prostate cancer, H2A.Z and its acetylated form are implicated in oncogenes' upregulation. SIRT1, which may act either as tumor suppressor or oncogene, reduces H2A.Z levels in cardiomyocytes, via proteasome-mediated deg...

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Bibliografski detalji
Glavni autori: Baptista, Tiago, Graça, Inês, Sousa, Elsa J., Oliveira, Ana I., Costa, Natália R., Costa-Pinheiro, Pedro, Amado, Francisco, Henrique, Rui, Jerónimo, Carmen
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2013
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858554/
https://ncbi.nlm.nih.gov/pubmed/24127549
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