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15 years of genetic approaches in vivo for addiction research: opioid receptor and peptide gene knockout in mouse models of drug abuse

The endogenous opioid system is expressed throughout the brain reinforcement circuitry, and plays a major role in reward processing, mood control and the development of addiction. This neuromodulator system is composed of three receptors, mu, delta and kappa, interacting with a family of opioid pept...

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Detalhes bibliográficos
Main Authors: Charbogne, Pauline, Kieffer, Brigitte L., Befort, Katia
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858501/
https://ncbi.nlm.nih.gov/pubmed/24035914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.08.028
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