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Central Memory CD8 T Cells in Aged Mice Are Virtual Memory Cells

The number of memory phenotype CD8 T cells increases dramatically with aging in both humans and mice. However, the mechanism for this is unknown. The prevailing hypothesis is that memory T cells accumulate with aging as a result of lifelong antigenic stimulation. However, data supporting this suppos...

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Bibliografiske detaljer
Main Authors: Chiu, Bo-Chin, Martin, Brian E., Stolberg, Valerie R., Chensue, Stephen W.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858473/
https://ncbi.nlm.nih.gov/pubmed/24227783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302509
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