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Structural Insights into the Globular Tails of the Human Type V Myosins Myo5a, Myo5b, and Myo5c

Vertebrate type V myosins (MyoV) Myo5a, Myo5b, and Myo5c mediate transport of several different cargoes. All MyoV paralogs bind to cargo complexes mainly by their C-terminal globular domains. In absence of cargo, the globular domain of Myo5a inhibits its motor domain. Here, we report low-resolution...

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Autori principali: Velvarska, Hana, Niessing, Dierk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858360/
https://ncbi.nlm.nih.gov/pubmed/24339992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082065
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