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Centrosomal Localisation of the Cancer/Testis (CT) Antigens NY-ESO-1 and MAGE-C1 Is Regulated by Proteasome Activity in Tumour Cells

The Cancer/Testis (CT) antigen family of genes are transcriptionally repressed in most human tissues but are atypically re-expressed in many malignant tumour types. Their restricted expression profile makes CT antigens ideal targets for cancer immunotherapy. As little is known about whether CT antig...

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Detalhes bibliográficos
Main Authors: Pagotto, Anna, Caballero, Otavia L., Volkmar, Norbert, Devalle, Sylvie, Simpson, Andrew J. G., Lu, Xin, Christianson, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858345/
https://ncbi.nlm.nih.gov/pubmed/24340093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083212
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