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Benzo(a)Pyrene Causes PRKAA1/2-Dependent ID2 Loss in Trophoblast Stem Cells
Benzo(a)pyrene (BaP), a cigarette smoke component, is metabolized to diol esters (BPDE) that bind to DNA and form mutagenic BPDE-DNA adducts. BaP activates stress enzymes including stress-activated protein kinase/jun kinase (MAPK8/9) in embryos, AMP-activated protein kinase alpha1/2 subunits (PRKAA1...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3858327/ https://ncbi.nlm.nih.gov/pubmed/20422711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrd.21178 |
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