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Early Life Manganese Exposure Upregulates Tumor-Associated Genes in the Hypothalamus of Female Rats: Relationship to Manganese-Induced Precocious Puberty

Prepubertal exposure to low, but elevated levels of manganese (Mn) can induce increased secretions of puberty-related hormones resulting in precocious pubertal development in female rats. These events are due to an action of the element within the hypothalamus to induce the secretion of gonadotropin...

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Autori principali: Srivastava, Vinod K., Hiney, Jill K., Dees, William L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858189/
https://ncbi.nlm.nih.gov/pubmed/23997110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft195
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