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A targeted enzyme approach to sensitization of tyrosine kinase inhibitor-resistant breast cancer cells

Gefitinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) of potential use in patients with breast cancer. Unfortunately, in clinical studies, gefitinib is often ineffective indicating that resistance to EGFR inhibitors may be a common occurrence in cancer of the breast...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Giordano, Courtney R., Mueller, Kelly L., Terlecky, Laura J., Krentz, Kendra A., Bollig-Fischer, Aliccia, Terlecky, Stanley R., Boerner, Julie L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858180/
https://ncbi.nlm.nih.gov/pubmed/22687878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2012.06.001
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