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HER-2 Signaling, Acquisition of Growth Factor Independence, and Regulation of Biological Networks Associated with Cell Transformation

Activated oncogenes are the dominant drivers of malignant progression in human cancer, yet little is known about how the transformation from proto-oncogene to activated oncogene drives the expression of transformed phenotypes. An isogenic model of HER-2–mediated transformation of human mammary epith...

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Bibliografiske detaljer
Main Authors: Bollig-Fischer, Aliccia, Dziubinski, Michele, Boyer, Alaina, Haddad, Ramsi, Giroux, Craig N., Ethier, Stephen P.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858175/
https://ncbi.nlm.nih.gov/pubmed/20736364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1529
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