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Control of non-apoptotic developmental cell death in C. elegans by a polyglutamine-repeat protein

Death is a vital developmental cell fate. In Caenorhabditis elegans, programmed death of the linker cell, which leads gonadal elongation, proceeds independently of caspases and apoptotic effectors. To identify genes promoting linker-cell death, we performed a genome-wide RNA interference screen. We...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Blum, Elyse S., Abraham, Mary C., Yoshimura, Satoshi, Lu, Yun, Shaham, Shai
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858082/
https://ncbi.nlm.nih.gov/pubmed/22363008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1215156
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