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Matrix-assisted Laser Desorption/Ionization Time of Flight (MALDI-TOF) Mass Spectrometric Analysis of Intact Proteins Larger than 100 kDa

Effectively determining masses of proteins is critical to many biological studies (e.g. for structural biology investigations). Accurate mass determination allows one to evaluate the correctness of protein primary sequences, the presence of mutations and/or post-translational modifications, the poss...

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Bibliographic Details
Main Authors: Signor, Luca, Boeri Erba, Elisabetta
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857990/
https://ncbi.nlm.nih.gov/pubmed/24056304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50635
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