Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Fairness of skin, UV sensitivity and skin cancer risk all correlate with the physiologic function of the melanocortin 1 receptor, a G(s)-coupled signaling protein found on the surface of melanocytes. Mc1r stimulates adenylyl cyclase and cAMP production which, in turn, up-regulates melanocytic produc...

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Detaylı Bibliyografya
Asıl Yazarlar: Amaro-Ortiz, Alexandra, Vanover, Jillian C., Scott, Timothy L., D'Orazio, John A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MyJove Corporation 2013
Konular:
Medicine
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857937/
https://ncbi.nlm.nih.gov/pubmed/24056496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50670
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