Loss of neurotensin receptor-1 disrupts the control of the mesolimbic dopamine system by leptin and promotes hedonic feeding and obesity()

Neurons of the lateral hypothalamic area (LHA) control motivated behaviors such as feeding and ambulatory activity, in part by modulating mesolimbic dopamine (DA) circuits. The hormone, leptin, acts via the long form of the leptin receptor (LepRb) in the brain to signal the repletion of body energy...

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Detalhes bibliográficos
Main Authors: Opland, Darren, Sutton, Amy, Woodworth, Hillary, Brown, Juliette, Bugescu, Raluca, Garcia, Adriana, Christensen, Lyndsay, Rhodes, Christopher, Myers, Martin, Leinninger, Gina
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857883/
https://ncbi.nlm.nih.gov/pubmed/24327958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.07.008
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