Tumor versus Stromal Cells in Culture—Survival of the Fittest?

Two of the signature genetic events that occur in human gliomas, EGFR amplification and IDH mutation, are poorly represented in experimental models in vitro. EGFR amplification, for example, occurs in 40 to 50% of GBM, and yet, EGFR amplification is rarely preserved in cell cultures derived from hum...

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Главные авторы: Talasila, Krishna M., Brekka, Narve, Mangseth, Kjersti, Stieber, Daniel, Evensen, Lasse, Rosland, Gro V., Torsvik, Anja, Wagner, Marek, Niclou, Simone P., Mahesparan, Rupavathana, Vintermyr, Olav K., Bjerkvig, Rolf, Nigro, Janice M., Miletic, Hrvoje
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857854/
https://ncbi.nlm.nih.gov/pubmed/24349039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081183
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